Thursday, February 28, 2013

Anastacia Diagnosed With Breast Cancer for Second Time, Cancels ...

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Singer Anastacia has canceled her upcoming European tour after being diagnosed with breast cancer for the second time.

The 44-year-old Chicago-born pop star, best known for her 1999 smash, "I'm Outta Love," was scheduled to launch her upcoming tour in London on April 6, but has opted go cancel the tour instead, so that she may focus on fighting the disease.

"Anastacia has sadly been diagnosed with breast cancer for the second time after having successfully survived her 2003 battle with the disease. Consequently she has been forced to cancel all performances, tours and any travel from now until further notice," reads a post on her Facebook page

I feel so awful to be letting down all my amazing fans who were looking forward to 'It's A Man's World Tour'. It just breaks my heart to disappoint them," the singer added, in a personal note.


Watch Anastacia's "I Can Feel You" Video

Source: http://blog.music.aol.com/2013/02/27/anastacia-diagnosed-with-breast-cancer/

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Mastermind behind Great Train Robbery dies at 81

LONDON (Reuters) - The mastermind behind Britain's "Great Train Robbery", a 1963 heist that turned its perpetrators into celebrities, has died aged 81, local media reported on Thursday.

Bruce Reynolds died in his sleep at his home in London after a period of ill health, reports from news media which included the BBC said, citing comments from Reynolds's son, Nick.

His death comes just months before the 50th anniversary of the "Great Train Robbery", that was at the time Britain's largest robbery.

In August 1963, Reynolds, along with an 11-member gang, tampered with railway track signals and stopped a Royal Mail night train travelling from Glasgow to London carrying letters parcels and large amounts of cash.

Reynolds and his men stormed the train and made off with 2.6 million pounds, equivalent to about 40 million pounds in today's money.

Train driver Jack Mills was struck over the head during the robbery. He died seven years later and many people believed the injuries he sustained during the heist contributed to his death.

Most of the gang were caught and given prison sentences totalling more than 300 years but Reynolds evaded capture, fleeing Britain with his wife and son. He spent five years as a fugitive in places as far afield as Canada and Mexico.

On his return to Britain Reynolds was caught by police and sentenced 25 years in prison for the train heist, of which he served just 10.

Reynolds later found fame as an author after penning his memoirs titled "Autobiography of a Thief" and became a consultant on a crime film.

His accomplice Ronnie Biggs achieved similar notoriety after he escaped from the prison where he was serving a 30-year jail sentence for his part in the robbery.

Biggs spent 36 years on the run, leading a playboy lifestyle in South America, before finally surrendering to British police in 2001. Biggs was freed in 2009 on health grounds.

(Reporting by Clare Hutchison)

Source: http://news.yahoo.com/mastermind-behind-uks-great-train-robbery-dies-81-142709566.html

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Wednesday, February 27, 2013

7 Personal Finance Myths Debunked - Business Insider

Think you're financially savvy?

When it comes to their personal finances, people carry around notions all their lives that may or may not be valid.

For example, you've heard that money can't buy you love, but can it buy happiness?

Most people believe that it can't -- but science may prove them wrong.

Here are seven personal finance myths that happen to be everyday beliefs about the way we consider and handle money.

Many of these myths fool even the smartest of savers. The latest research will help you discern the facts and see through the smoke.

This story was originally published by?Bankrate.

Source: http://www.businessinsider.com/7-personal-finance-myths-debunked-2013-2

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Egypt Lake Nasser Cruises

Egypt Lake Nasser Cruises

Your Lifetime Tour through the Legends of Nubia
Going more to the south of Aswan stands Lake Nasser, an enormous reservoir formed by the building of the high dam in 1971. Here you will discover the lesser known temples as well as Abu Simbel , Egypt's greatest monument after the Pyramids. Lake Nasser cruises are those boats sailing in the River Nile between Aswan and Abu Simbel with different schedules, different accommodation length and different cruise facilities according to the Lake Nasser cruises Category 5 star, 5 star Deluxe and 5 star Luxury cruises. Albaraa Travel Group offer a perfect selection of cruise holidays combining Lake Nasser cruises and River Nile cruises with sightseeing tours to the major sights of Egypt. We offer many lake Nasser cruises and stay options, of lengths from (4, 5, 8) days. Itineraries include, Wadi El Seboua and the temple of Ramses II, Kasr Ibrim and the relocated temple of Amada. Also there is a good opportunity to attend the Sound and light show at Abu Simbel Temples at night.

How to Join our Lake Nasser Cruise:

1) Fly from Cairo to Aswan or to Abu Simbel to join our Lake Nasser cruise tours.
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Places to visit while cruising in Lake Nasser
Visit the Kalabsha Temple, Beit El Wali, and the Kiosk of Kertassi, Wadi El Seboua, the Temple of Dakka and Temple of Meharakka and the temple of Ramses II, Kasr Ibrim and the relocated temple of Amada as well as the tomb of Penout. Also there is a good opportunity to attend the Sound and light show at Abu Simbel Temples at night. Egypt lake Nasser cruises, cruise in Lake Nasser Egypt, Lake cruises Egypt, lake Nasser cruise hot offers, lake Nasser cruise hot deals, combine Nile and lake cruise, Egypt lake cruise holidays, cruising lake Nasser, Nubian lake cruises, Nubian cruises. Lake cruise stay

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Source: http://www.articlesnatch.com/Article/Egypt-Lake-Nasser-Cruises/4457148

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Drop in Taliban attacks incorrect

WASHINGTON (AP) ? The U.S.-led military coalition in Afghanistan incorrectly reported a decline in Taliban attacks last year, and officials said Tuesday that there was actually no change in the number of attacks on international troops from 2011 to 2012.

The corrected numbers ? from the original reports of a 7 percent decline to one of no change ? could undercut the narrative promoted by the international coalition and the Obama administration of an insurgency in steep decline.

A coalition spokesman, Jamie Graybeal, attributed the miscounting to clerical errors and said the problem does not change officials' basic assessment of the war.

The 7 percent figure had been included in a report posted on the coalition's website in late January as part of its monthly update on trends in security and violence. It was removed from the website recently without explanation. After The Associated Press asked last week about the missing report, coalition officials said they were correcting the data and would re-publish the report in coming days.

U.S. and allied officials have often cited declining violence as a sign that the Taliban has been degraded and that Afghan forces are in position to take the lead security role when the last U.S. combat troops leave Dec. 31, 2014.

[Related: America's homegrown terrorists]

In mid-December, Defense Secretary Leon Panetta said "violence is down," in 2012, and that Afghan forces "have gotten much better at providing security" in areas where they have taken the lead role. He said the Taliban can be expected to continue to attack, "but overall they are losing."

On Tuesday, Pentagon spokesman George Little said Panetta was "concerned to learn of the errors" and was only very recently briefed on the matter.

"This particular set of metrics doesn't tell the full story of progress against the Taliban, of course, but it's unhelpful to have inaccurate information in our systems," Little said.

The Taliban have lost a good deal of territory since a 2010 surge of U.S. forces in the southern provinces of Helmand and Kandahar, and they failed to recover it during the last two fighting seasons. Even so, they are resilient, and they are expected to severely test Afghan forces as the U.S. and its coalition partners step further into the background this year and complete their combat mission next year.

Graybeal did not fully explain ISAF's erroneous reporting of 2012 Taliban attacks. It was not clear, for example, at what point the data errors began or who discovered them.

[Related: U.S. troops engaged in 'torture' and murder?]

"During a quality control check, ISAF recently became aware that some data was incorrectly entered into the database that is used for tracking security-related incidents across Afghanistan," Graybeal said from Kabul, speaking for the International Security Assistance Force, or ISAF.

Graybeal said an audit determined that portions of the data from unilateral Afghan military operations were "not properly reflected" in the trends ISAF had reported in its monthly updates.

"After including this unilateral ANSF (Afghan National Security Force) data into our database, we have determined that there was no change in the total number of EIAs (enemy initiated attacks) from 2011 to 2012," Graybeal said.

"This was a record-keeping error that we recognized and have now corrected," he added.

The coalition defines enemy initiated attacks as attacks by small arms, mortars, rockets and improvised explosive devices, or IEDs. But it does not include IEDs that are found and cleared before they explode.

Trends in Taliban attacks are one yardstick used by ISAF to measure war progress. Others include the state of security in populated areas, the number of coalition and Afghan casualties, the degree to which civilians can move about freely, and the performance of Afghan security forces.

Graybeal said even though the number of 2012 Taliban attacks was unchanged from 2011, "our assessment of the fundamentals of campaign progress has not changed. The enemy is increasingly separated from the population and the ANSF are currently in the lead for the vast majority of partnered operations."

Source: http://news.yahoo.com/ap-newsbreak-drop-taliban-attacks-incorrect-121946153--politics.html

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Tuesday, February 26, 2013

HBT: Aaron had big ideas in commissioner pitch

Yesterday I linked that story in which Ernie Banks talked about Hank Aaron ?applying? to be the commissioner of baseball once upon a time. Last night my friend Jess Lemont sent me a news article from 1983 with some details about it. ?Seems that was when he announced his desire to replace Bowie Kuhn, who had just recently announced his resignation under pressure from the owners.

Obviously Peter Ueberroth?got the job. He then proceeded to break the Collective Bargaining Agreement and the law with his collusion schemes. That ended up costing the players and the owners hundreds of millions of dollars which in turn led to double expansion in the 1990s to pay for it. ?Good going, Pete!

What might have happened if Aaron had gotten the job instead? My theory: the owners either would not have engaged in any greedy illegal schemes or else Aaron would have resigned in protest had they tried. ?Short of that, though there there?s at least some evidence to suggest that, if he were commissioner, he might not have taken too different a course than Bud Selig took when he got the job in the early 90s. From the article, Aaron?s response when asked what changes he might institute as?commissioner:

?A major one is Interleague play. We are denying fans of both leagues the opportunity to see outstanding players and teams.?

He added that he?d push for a uniform DH rule, though he doesn?t say if he?d prefer all DH or no DH. He also pushed for two-team expansion to get the leagues up to 14 teams each. Oh, and there?s this:

Aaron, currently the Braves? director of player development, said he is not anti-player, but he supports placing a salary cap on teams? payrolls.

He goes on to talk about how the Twins can?t compete without a salary cap because Calvin Griffiths doesn?t have the money to sign free agents. Never mind that, within eight years and a couple of months the Twins will have won two World Series. Whatever the case, this is on all fours with Selig?s talking points from 1994 through around 2002 or so, which led to the most destructive work stoppage in the sports? history and nearly led to another.

Notably, Selig ? a longtime close friend of Aaron ? led the search committee that ultimately settled on Ueberroth?over Aaron. He also promised Aaron the chance to talk to the committee. Given that they remain friends I?m guessing that it wasn?t him, but rather, other owners who ?laughed? at Aaron?s candidacy, as Banks said.

Neat stuff. Thanks Jess!

Source: http://hardballtalk.nbcsports.com/2013/02/26/commissioner-hank-aaron-would-have-instituted-interleague-play-tried-to-impose-a-salary-cap/related/

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Quvenzhan? Wallis to play title role in "Annie" movie

NEW YORK (Reuters) - Nine-year-old Oscar nominee Quvenzhan? Wallis will play the title role in "Annie," Sony's Columbia Pictures announced on Sunday.

"Annie" is due to hit theaters in 2014 during the winter holiday season, and is based on the stage play about an orphan's adventures in finding her family and a better life while overcoming the schemes of orphanage mistress Miss Hannigan.

President of production at Columbia Pictures Hannah Minghella expressed confidence in Wallis' talent and star power.

"With the recent Academy Award nomination and critical acclaim, Quvenzhan? Wallis is a true star and we believe her portrayal as Annie will make her a true worldwide star," she said.

"She is an extraordinary young talent with an amazing range, not only as an actress but as a singer and dancer, and we can't wait for audiences to further discover her."

Among the film's co-producers are Will Smith, Jada Pinkett Smith and Shawn "Jay-Z" Carter. Carter's 1998 Grammy-winning album "Vol. 2... Hard Knock Life" contains a hip-hop version of "It's a Hard Knock Life," a song from the original Broadway musical "Annie."

The hit musical was first made into a film starring Carol Burnett as Miss Hannigan in 1982. A made-for-TV version with Kathy Bates in the same role aired on ABC in 1999, and earned two Emmy awards.

Wallis is the youngest actress to ever be nominated for a Best Actress Oscar. She was nominated for her role as Hushpuppy in indie drama "Beasts of the Southern Wild," which also earned a nod for Best Picture. "Beasts" is Wallis' first acting job.

Among her other firsts, she will also be the first African-American actress to play Annie, who has been traditionally portrayed as a freckle-faced redhead.

Later this year, she will star alongside Brad Pitt and Michael Fassbender in Steve McQueen's historical drama "Twelve Years a Slave," based on the book by Solomon Northup.

(Editing by Eric Walsh and Jackie Frank)

Source: http://news.yahoo.com/quvenzhan-wallis-play-title-role-annie-movie-213840204--finance.html

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Travel insurance get-out clauses - February - 2013 - Which? News

26 February 2013

Which? research has revealed the most common reasons why travel insurers turn down claims because of clauses in the small print.

We found members were getting what they felt were legitimate claims turned down because of small print covering the health of relatives, how an incident was reported, how belongings were monitored, and taxes.

We looked at details of policies after we asked more than 9,000 Which? members about their experience of making insurance claims. Of the members who had made travel insurance claims in the previous two years, 10% had a claim rejected.?

Travel insurance claims

This was higher than any other sector and nearly double that of home and phone sectors, which had the next highest rate of rejection.?

Travel insurance also had a lower rate of satisfaction with claims, scoring 66% compared to the 75% average of the other sectors we looked at.

Many members complained about their treatment when they had to cancel a holiday because a relative was ill. They had claims rejected because the insurer argued that the relatives' conditions were pre-existing and should have been declared.

Medical insurance claims

This included one case involving what doctors confirmed was a 'sudden and unexpected' death of a customer's son-in-law the day before the holiday was due to start.

Some insurers say medical conditions of relatives as distant as cousins must be declared on buying a policy. We think this is unreasonable as it requires consumers to ask all their extended family about their health before buying a policy. Other insurers say you must declare only relatives' conditions you are aware of. We think this is slightly better.

Theft and loss claims

Another common reason for rejection was insurers saying customers had not reported a lost or stolen item to police within 24 hours. One member had a claim turned down for that reason even though they lost their glasses on a cruise ship.

It's reasonable to ask for evidence that an item is lost, but we don't think lost items should have to be reported to police within 24 hours. We prefer insurance terms that say lost or stolen items should be reported to relevant authorities as soon as possible.

Insurers also rejected claims because they said stolen items were not properly supervised. This included items that were only a few feet away from a customer on a crowded train, and others that were out of sight for only a second in a hotel.

Lost baggage claims

Insurers have to be reasonable when they decide what is unattended, and the Financial Services Ombudsman has upheld complaints against insurers who have been too strict - including one who refused to pay a claim for baggage that was lost after it was given to a hotel porter.

Many members who had to cancel a flight complained about insurers refusing to pay for the taxes element of the fare, which in one case made up nearly half of a ?1,100 ticket. When insurers do this, it means customers have to claim the taxes back from airlines, who normally charge an admin fee, which can sometimes be as much as the tax.

Although it may be reasonable for insurers to ask customers to try the airline first, if the airline refuses or charges an admin fee that cancels out the refund, the Financial Services Ombudsman thinks insurers should pay.

We advise checking insurers terms and conditions in these areas before you buy a policy. Ideally, you should check all the terms and conditions before buying a policy.

A Which? spokesperson said, 'If you have a claim rejected, the financial ombudsman can take up your case if an appeal with the insurer fails.'

More on this...

Source: http://www.which.co.uk/news/2013/02/travel-insurance-get-out-clauses--311345/

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Women's Exposure to Chemicals May Explain Unexpected Breast Cancer

Breast Cancer 3-Day Women attend a fundraiser for breast cancer in San Francisco. Image: Flickr/cpurl

Deep in a laboratory freezer, 100,000 vials of blood have been frozen for the better part of five decades.

For scientist Barbara Cohn, it?s a treasure trove. Collected from more than 15,000 San Francisco Bay Area women after they gave birth in the 1960s, each vial of blood holds a woman?s lifetime of secrets.

Scientists say these vials could help them unravel one of the most enduring medical mysteries: Why do some women, with no family history, develop breast cancer?

The blood bears the chemical signature of environmental pollutants, some long banned, that the women were exposed to decades ago. Cohn, who directs the research in Berkeley, Calif., believes these early-life exposures may hold the key to understanding a woman's risk of breast cancer today.

The women's blood is being tested for traces of dozens of pollutants???used by industry and found in many consumer products???that can impersonate estrogen and other hormones. The theory is that early exposure to these chemicals, even before birth, inside the mother?s womb, may fundamentally alter the way that breast tissues grow, triggering cancer decades later.

Cancer patients and their doctors have long puzzled over what factors in a woman?s environment may raise her risk of breast cancer. One of every eight women in the United States is diagnosed with breast cancer during her lifetime, with more than 232,000 new cases diagnosed yearly, according to the American Cancer Society. Only five to 10 percent can be accounted for by genetics; other known risk factors include age, obesity and low physical activity.

Earlier this month, a science advisory panel?urged the federal government to fund more projects aimed at uncovering the environmental causes of breast cancer because eliminating these factors may provide the greatest opportunity to prevent it.

It?s particularly vexing for scientists because it?s difficult to unlock a woman?s exposures during her most critical times for breast development: in the womb and during puberty and pregnancy.

?As researchers looking at adult outcomes of disease processes such as breast cancer, one of the biggest challenges we face is trying to get a handle on prenatal exposures and what is going on in the prenatal environment,? said Shanna Swan, an environmental health scientist at Mount Sinai School of Medicine in New York.

Many scientists have been looking for connections between various environmental exposures and the disease???with mixed results. Some findings suggest links to a few chemicals, including the banned pesticide DDT. But others have found no link.

For example, experts from the American Cancer Society, reviewing previous studies, in 2002 found no association between breast cancer and chlorinated chemicals including DDT.

And in 2011, an institute of the National Academies of Sciences reported ?a possible link? between breast cancer and some common ingredients of vehicle exhaust, benzene and 1,3-butadiene. But the report?said the jury is still out for most other widespread chemicals, such as pesticides, ingredients of cosmetics and bisphenol A (BPA).

Source: http://rss.sciam.com/click.phdo?i=4be39565ab7b234106a46966811520a8

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Sunday, February 24, 2013

Williams scores 46 to lead New Mexico past CSU

FORT COLLINS, Colo. (AP) ? With 9 minutes left, New Mexico guard Kendall Williams trudged to the bench with a career-high 28 points ? and four fouls.

While he caught his breath, No. 22 Colorado State built a six-point lead over the 16th-ranked Lobos.

Moby Arena was rocking and the Rams were rolling, about to extend the nation's third-longest home winning streak to 28 games.

Williams had other things in mind ? and 18 points left to score.

"Luckily, some shots went in," said the junior guard from Rancho Cucamonga, Calif., who finished with a career-best 46 points ? almost double his previous career high of 24 ? in leading New Mexico to a 91-82 win Saturday.

Williams set a Mountain West Conference record with 10 3-pointers and his 46 points were the most in the 47-year-old arena, topping the 44 scored by Portland State's Freeman Williams on Nov. 29, 1975.

"He should be hands-down player of the week, I would think," Lobos coach Steve Alford deadpanned.

Williams helped the Lobos overcome that 70-64 deficit at the 6-minute mark by hitting a trio of 3-pointers, a dunk and seven free throws down the stretch as New Mexico outscored the Rams 27-12.

"He got on a roll today," Alford said. "And it was a 40-minute roll."

Actually, it was a 33-minute roll. He spent seven minutes on the bench in foul trouble.

"That's what's really impressive," Alford said. "He sat about a four-minute stretch there in the second half and still scores and does what he does. It's pretty amazing. But he did a great job in that last six minutes not picking up that fifth" foul.

Center Alex Kirk added 19 points and 10 rebounds for the Lobos (23-4, 10-2), who increased their lead in the conference race to two games over the Rams (21-5, 8-4).

Colton Iverson had 26 points and 15 boards for the Rams, who looked like they were going to move into a first-place tie atop the standings after taking a 70-64 lead at the 6-minute mark.

Williams' treys highlighted a 14-2 run that gave New Mexico a 78-72 lead before the Rams sent the Lobos to the line over the final two minutes.

"Well, that was a special night to watch," Alford said. "I told him that. I said I never had a 10-3 game, I never got to 46. Forty-two was the most I ever scored and eight 3s was the most I ever made in a game."

"There's not too many one-ups you can get on Coach Alford, especially in scoring," Williams said. "I might be on top of the world for the rest of the weekend."

Williams' previous career best was 24 points against Indiana State and New Mexico State earlier this season.

"The players kept feeding me the ball," said Williams, who had 15 family members, including his grandmother, in the stands. "It was really just a team effort, some of the shots I hit were tough. But if the teammates didn't put me in position and the coaches didn't put me in position, I wouldn't have had quite the night I had."

The Rams blamed themselves for Williams' big game.

"We had no answer for him," Rams coach Larry Eustachy said. "... He was completely unstoppable. I want to see film on how many of those shots were contested."

His bet is that not many were.

The Rams, who gave up 45 points to Air Force's Michael Lyons a week earlier, left Williams open early on while locking down Tony Snell, who scored 10 points Saturday after getting 23 in their first meeting last month.

"He hadn't been shooting well this year," Dorian Green said. "We gave him some uncontested looks, let him get hot. Guys are too good in our league to do that."

"We gave him open looks early," Wes Eikmeier added. "He got hot and then he was feeling it the rest of the night."

Green (20) and Eikmeier (22) gave the Rams three 20-point scorers in their losing effort. Eikmeier scored 11 straight to put the Rams ahead 55-50.

The Lobos quieted the crowd with a 12-6 run to regain the lead at 62-61, but Williams, less than a minute after returning to the lineup, was whistled for his fourth foul and took a seat at the nine-minute mark.

"I was real mad," Williams said. "My emotions were high, but (assistant coach Craig) Neal came over while Coach Alford was doing his thing and calmed me down and says, 'You're going to have to bring it home, kid. Don't foul and get the shots that you need.' And that's exactly what I did."

The Rams were coming off a two-point loss at UNLV on Wednesday night that snapped their six-game winning streak, which began after a 66-61 loss to the Lobos in Albuquerque last month.

They hadn't lost at home since Nov. 11, 2012, to Southern Miss., which was coached at the time by Eustachy, who took the Rams job last offseason.

Williams' 10th 3-pointer ? in 13 tries ? broke the conference mark of nine set by several players, most recently UNLV's Chace Stanback against Central Arkansas on Dec. 28, 2011. It was a difficult shot from the right corner.

"Why not? Just throw it up there, had hit a few already," Williams said. "With the hoop the size it was tonight and the rhythm I was feeling, it just felt like I had to throw that one up."

___

Follow Arnie Melendrez Stapleton on Twitter: http://twitter.com/arniestapleton

Source: http://news.yahoo.com/williams-scores-46-lead-mexico-past-csu-011006077--spt.html

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Kohli, Dhoni hit tons, India 403 for 7

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Chennai: Virat Kohli smashed his fourth Test hundred, while skipper Mahendra Singh Dhoni hit his sixth as India reached 403 for seven post tea session on the third day of the first cricket Test against Australia here on Sunday.

In reply to Australia?s 380 all out, India put themselves in a good position with Kohli?s patient 107 and Dhoni still playing at 121 not out from 145 balls.

Also notable was the magnificent half-century by Sachin Tendulkar (81).

At the break, Dhoni was holding fort with R Ashwin (3) giving him company.

India scored at a decent pace to be 263 for four at lunch, but after the break, the innings accelerated with Kohli and Dhoni breaking free against an attack that never looked very threatening.

Kohli eventually fell to Nathan Lyon, who was rewarded for his perseverance after grabbing Tendulkar?s wicket in the morning session.

However, the breakthrough came only after Kohli and Dhoni had put on 128 runs for the fifth wicket and that too at rapid a pace.

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Source: http://www.mynews.in/News/kohli_dhoni_hit_tons_india_403_for_7_N543207.html

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Vatican blasts media for influencing pope election with 'false' reports

VATICAN CITY (AP) ? The Vatican lashed out Saturday at the media for what it said has been a run of defamatory and false reports before the conclave to elect Pope Benedict XVI's successor, saying they were an attempt to influence the election.

Italian newspapers have been rife with unsourced reports in recent days about the contents of a secret dossier prepared for the pope by three cardinals who investigated the origins of the 2012 scandal over leaked Vatican documents.

The reports have suggested the revelations in the dossier, given to Benedict in December, were a factor in his decision to resign. The pope himself has said merely that he doesn't have the "strength of mind and body" to carry on and would resign Feb. 28.

On Saturday, a day before Benedict's final Sunday blessing in St. Peter's Square, the Vatican secretariat of state said the Catholic Church has for centuries insisted on the independence of its cardinals to freely elect their pope ? a reference to episodes in the past when kings and emperors vetoed papal contenders or prevented cardinals from voting outright.

"If in the past, the so-called powers, i.e., States, exerted pressures on the election of the pope, today there is an attempt to do this through public opinion that is often based on judgments that do not typically capture the spiritual aspect of the moment that the church is living," the statement said.

"It is deplorable that as we draw closer to the time of the beginning of the conclave ... that there be a widespread distribution of often unverified, unverifiable or completely false news stories that cause serious damage to persons and institutions."

Vatican spokesman the Rev. Federico Lombardi was asked how specifically the media was trying to influence the outcome; Lombardi didn't respond directly, saying only that the reports have tended to paint the Curia in a negative light "beyond the considerations and serene evaluations" of problems that cardinals might discuss before the conclave.

Some Vatican watchers have speculated that because the Vatican bureaucracy is heavily Italian, cardinals might be persuaded to elect a non-Italian, non-Vatican-based cardinal as pope to try to impose some reform on the Curia.

While Lombardi has said the reports "do not correspond to reality," the pope and some of his closest collaborators have recently denounced the dysfunction in the Apostolic Palace.

Cardinal Gianfranco Ravasi, for example, criticized the "divisions, dissent, careerism, jealousies" that afflict the Vatican bureaucracy. He made the comments Friday, the penultimate day of the Vatican's weeklong spiritual exercises that were attended by the pope and other officials. Ravasi, himself a papal contender, was chosen by Benedict to deliver daily meditations and on Saturday Benedict praised him for his "brilliant" work.

The divisions Ravasi spoke of were exposed by the documents taken from the pope's study by his butler and then leaked by a journalist. The documents revealed the petty wrangling, corruption and cronyism and even allegations of a gay plot at the highest levels of the Catholic Church.

The three cardinals who investigated the theft had wide-ranging powers to interview even cardinals to get to the bottom of the dynamics within the Curia that resulted in the gravest Vatican security breach in modern times.

Benedict too has made reference to the divisions in recent days, deploring in his final Mass as pope on Ash Wednesday how the church is often "defiled" by attacks and divisions from within. Last Sunday, he urged its members to overcome "pride and egoism."

On Saturday, in his final comments to the Curia, Benedict lamented the "evil, suffering and corruption" that have defaced God's creation. But he also thanked the Vatican bureaucrats for having helped him "bear the burden" of his ministry with their work, love and faith these past eight years.

The Vatican's attack on the media echoed its response to previous scandals, where it has tended not to address the underlying content of accusations, but has diverted attention away. During the 2010 explosion of sex abuse scandals, the Vatican accused the media of trying to attack the pope; during the 2012 leaks scandal, it accused the media of sensationalism without addressing the content of the leaked documents.

___

Follow Nicole Winfield at www.twitter.com/nwinfield

Source: http://news.yahoo.com/vatican-blasts-false-pre-conclave-reporting-130526801.html

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Symbolic wedding at Union Bay Gaol

Published: February 21, 2013 4:00 PM
Updated: February 21, 2013 4:36 PM

The Second World War was raging in Europe, Canada was at war with Germany.

In 1939, three young Germans were in United States illegally. The Americans, although they had not yet entered the war, wanted all aliens gone or imprisoned.

In California, the three young men got passage on a Greek freighter heading to Siberia. The ship stopped at Union Bay to coal at the port.

The three decided they did not want to spend the war in Russia, so they jumped ship in Union Bay. After spending a wet night wandering around in the bush, they tried to hitch a ride on the highway.

The first car that came along was a police car. They were arrested and imprisoned in the Union Bay Gaol (jail) before being sent to a prisoner of war camp in Ontario, where they worked on a tomato farm. Six years passed before they were sent back to Germany.

One of the three, Fredrick Furber, married in Germany and brought his young family to Canada, being sponsored by the farmer where he had worked as a prisoner. He gradually moved west, ending up on Vancouver Island.

His son Richard had heard the story all his life, so he and his bride-to-be, Brenda Jeeves, thought it would be neat to honour his father by being married in the old gaol at Union Bay.

Janette Glover-Geidt, chair of the Union Bay Historical Society that owns and operates the gaol as a museum, appreciated the historical significance of the request and got caught up in the excitement.

Rev. Ray Brandon fell in with the plan and performed a lovely service for the couple on Feb. 13, 2013.

? Janette Glover-Geidt

'; } } document.getElementById("ad_unit").innerHTML += ad_unit; google_adnum += google_ads.length; return; } google_ad_client = 'pub-9774721429222771'; google_ad_output = 'js'; google_ad_channel ='3389691084'; google_max_num_ads = '4'; google_feedback = 'on'; google_ad_type = 'text'; google_adtest = 'on'; google_image_size = '300x250'; google_skip = '3'; // -->

Source: http://www.bclocalnews.com/community/192391431.html

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96% West of Memphis

All Critics (83) | Top Critics (21) | Fresh (80) | Rotten (3)

And justice for all? Hardly.

It tells the story of a terrible crime compounded by a grave injustice that's been remedied, but only in part, so it's impossible to have a single or simple response to the movie.

What sets this film apart from previous efforts to document the story is that Jackson and Walsh financed a private investigative team with legal and forensic experts who re-examined old evidence, conducted new interviews and found new witnesses.

Happy, sad, inspiring, infuriating, right and terribly wrong, all at the same time.

Berg's film is as much an indictment of the state of Arkansas' legal system as it is the prosecution.

Berg's film helps illuminate a case that should certainly be the shame of the state of Arkansas, and perhaps the criminal justice system of the entire United States.

West Of Memphis isn't afraid to show us the graphic nature of the crime and more importantly, it isn't afraid to point fingers at those whose actions deserve to be questioned.

It's reasonable to question whether the time and resources poured into this project might have been better spent highlighting a miscarriage of American justice that nobody knows about rather than one that enjoys a celebrity profile.

The most intense, nail-bitingly suspenseful thriller franchise "from the dark side" these days is not the product of a screenwriter's imagination.

The most intriguing and worthy aspect of this accomplished documentary is that it never lets anyone forget the biggest tragedy of the many threaded through this story - the helpless children who never deserved the brutal fate handed to them.

Somewhere along this narrative's mammoth timeline, examining the construction of modern social heroes became more important than the memories of three little boys.

Together with the rich material comprising interviews with family and friends, the footage shot in the various court rooms and at the crime scene is riveting

A powerful, touching and very infuriating documentary, although Berlinger and Sinofsky got there first and did it best

Amy Berg's West of Memphis does bring new information to light, which is why this somewhat procedural feature is so important.

In all, the director has assembled a powerful film, but the celebrity component feels rather unnecessary.

A frankly extraordinary document about the three innocent children who were murdered in West Memphis, Arkansas and the three innocent teenagers who spent 18 years in prison for the crime.

(Director Amy) Berg's doc is gripping, often infuriating, but in the end hopeful about the ability of truth and innocence to prevail thanks to the efforts of those who strive against all obstacles to uphold them.

The new film is largely a recap of the older ones, with more celebrity testimonials and fewer Metallica songs but little fresh insight into the miscarriage of justice it chronicles.

Extols the efforts of celebrities to win the release of three innocent men [and is] suspenseful when it's straightforward-the best CSI investigation that money can buy.

Nearly overwhelms you with hopelessness, if not an adrenaline rush of rage - even if you're familiar with the case.

It's a beautifully done piece of work in its own right, yet viewed beside the trilogy which preceded it, it comes across a bit like "Paradise Lost 3b - the Celebrity Edition."

No quotes approved yet for West of Memphis. Logged in users can submit quotes.

Source: http://www.rottentomatoes.com/m/west_of_memphis/

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Saturday, February 23, 2013

HTC One vs Sony Xperia Z: spec comparison

When the?HTC One launched, it became more than just the latest premium handset to enter the highly competitive mobile market - it staked a serious claim to the title of best smartphone in the world. ?The BlackBerry Z10 is an impressive enough effort, and while the?Apple iPhone 5?still boasts peerless design, it doesn't offer best of class hardware by 2013's heady standards. CES star the?Sony Xperia Z, however, is as cutting edge as it comes and a fitting sparring partner for HTC's latest hero phone. So how do the two new standard bearers stack up?

Size and weight

The slender but sturdy HTC One has a girth of 9.3mm and weighs 143g. Sony's Xperia Z is one of the thinnest devices available, sizing up at 7.9mm in depth but tipping the scales at a slightly heavier 146g.

Display

Both the HTC One and the Xperia Z look like they're really going to seduce the retinas, offering Full HD resolutions of 1,920 x 1,080 pixels on their LCD screens. By virtue of its smaller 4.7in display, the HTC One offers the sharper images at 469ppi, compared to the 5in Xperia Z's still-stunning 441ppi density.

Processor and battery

Under the hood, the HTC One packs Qualcomm's latest high-end SoC, the quad-core Snapdragon 600, comprised of Krait 300 CPUs clocked at 1.7GHz and an Adreno 320 GPU. Sony's new flagship sports an older Snapdragon S4 configuration with a processor speed of 1.5GHz. The HTC One features a 2,300mAh battery, while the Xperia Z features a 2,330mAh battery with a claimed 3G talk time of up to 11 hours.

Camera

The HTC One and Sony Xperia Z both claim to offer the best smartphone camera on the market, with the latter coming with a 13.1-megapixel Exmor RS sensor. ?HTC, on the other hand, has sought to distance itself from the traditional megapixel race by serving up a 4-megapixel CMOS sensor?consisting?of what the company refers to as?'UltraPixels'?- a marketing term to describe?the sensor's 2 micron pixels. These are larger than the photosites typically found on cameraphone sensors and should improve low-light shooting (bigger is better when gathering light). The Xperia Z's 2.2-megapixel front camera marginally shades the 2.1-megapixel?auxiliary?snapper found on HTC's new hero phone.

Storage and memory

The HTC One will be available in 32GB and 64GB models, though hardcore content hoarders won't be pleased that there's no option of expanding the device's capacity. The Xperia Z, by way of contrast, comes with a standard 32GB of on-board storage but offers a microSD card slot for cheap and easy augmentation. Both handsets also come with 2GB of RAM.

Connectivity and wireless

Both the HTC One and Sony Xperia Z support the LTE standard and will join the 4G party when they arrive in March. They also come with NFC technology, though neither can charge up wirelessly.

Software

In the Xperia Z and the HTC One, the Android platform has two of its brightest stars.?Die hard fans of Google's mobile OS will find themselves leaning towards the HTC device, however, as it is immediately upgradeable to Android 4.2 Jelly Bean. The One also features Sense 5.0, HTC's latest custom Android skin (pictured, below), which offers a number of neat features including Zoe Highlights, which transforms your otherwise static image gallery into flowing cinematic media. The Sony handset ships with Jelly Bean 4.1, with an upgrade to the newer version "planned."

Extras

Until the Xperia Z arrived, ITProPortal's spec comparisons didn't really need a section for special features, but the water and dust resistant Sony flagship changed all that. The HTC One offers some unique features courtesy of Sense 5.0: as well as Zoe Highlights, there's also Sense TV, which sees your handset double as a remote control via an integrated infrared technology. More of an obvious "extra," however, is the amusingly named BoomSound - HTC's audio setup includes two-built in amplifiers based on Beats Audio technology and a pair of front-facing speaker grills.

Price, availability and opinion

The HTC One will start shipping from 14 March and is currently available for pre-order via Phones 4u?- the handset can be had for naught on?contracts starting from ?36 a month. You can't officially?buy the One outright just yet, but established online retailer?Clove Technology lists the HTC One at ?510 SIM-free, if that's the route you want to take. ?The Sony Xperia Z broke cover at CES in January and will enjoy some quality European catwalk time at MWC ?2013, before hitting the UK on 1 March. The?Xperia Z can be pre-ordered via Amazon and off-contract pricing has been set around the ?500 mark.?

With both mobiles priced very similarly and offering a full suite of new-generation features, it's difficult to pick a presumptive winner - this is as close as spec showdowns come and it will surely develop into a grudge match. However, it looks like the boasts of HTC EMEA president Florian Seiche, if not indisputable, are very close to the truth. The HTC One may well be the "best phone ever made," but if not, it's certainly king of the smartphone pile for now: the Jelly Bean-based Sense 5.0 UI looks like offering one of the slickest custom user experiences around, while the handset's full aluminium build feels sturdy but slender at the same time.

While the 'UltraPixel' term will only serve to confuse, we thoroughly approve of the way HTC is moving away from the 'bigger is better' megapixel race in the camera department, too, and it's difficult to find better than the 1.7GHz quad-core Snapdragon 600 SoC featured under the hood. Ultimately, it just feels great to hold, and while definitive judgment can't be passed until we've put the two devices through their paces in full -?stay tuned for full HTC One and Sony Xperia Z reviews in the near future - we're fairly confident that the Taiwanese firm's latest and greatest effort will hold up admirably to more acute investigations.?

?

HTC One

Sony Xperia Z

Display

? ?

Screen size

4.7in

5in

Resolution

1,920 x 1,080 pixels

1,920 x 1,080 pixels

Pixel density

469ppi

441ppi

Type

TFT LCD

TFT LCD

Processor and battery

? ?

Family

Snapdragon 600

Qualcomm Snapdragon S4

CPU

Krait 300

Krait

Cores

Quad-core

Quad-core

Clock speed

1.7GHz

1.5GHz

GPU

Adreno 320

Adreno 320

Battery

2,300mAh

2,330mAh

Claimed 3G talk time

TBC

Up to 11 hours

Storage and memory

? ?

RAM

2GB

2GB

Internal storage

32GB / 64GB

16GB

microSD

No

Yes

Camera

? ?

Rear

?4-megapixel

13.1-megapixel

Video

1080p @ 30fps

1080p @ 30fps

Front

2.1-megapixel

2.2-megapixel

Wireless

? ?

Standard

4G LTE

4G LTE

Wi-Fi

802.11 a / b / g / n

802.11 b/g/n

NFC

Yes

Yes

Bluetooth

v4.0

v4.0

Integrated wireless charging

No

No

Dimensions

? ?

Size

137.4 x 68.2 x 9.3mm

139 x 71 x 7.9mm

Weight

143g

146g

Operating System

Android 4.2 Jelly Bean w/Sense 5.0

Android 4.1 Jelly Bean

Price (SIM-free)

?510 via Clove

?500 via Amazon

Source: http://feedproxy.google.com/~r/itproportal/rss/~3/iOhO1mXm0MU/

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Friday, February 22, 2013

NASA and JPL contribute to European Jupiter mission

Feb. 21, 2013 ? NASA has selected key contributions to a 2022 European Space Agency (ESA) mission that will study Jupiter and three of its largest moons in unprecedented detail. The moons are thought to harbor vast water oceans beneath their icy surfaces.

NASA's contribution will consist of one U.S.-led science instrument and hardware for two European instruments to fly on ESA's Jupiter Icy Moons Explorer (JUICE) mission. Jeffrey Plaut of NASA's Jet Propulsion Laboratory in Pasadena, Calif., will be the U.S. lead for the Radar for Icy Moon Exploration experiment. The radar experiment's principal investigator is Lorenzo Bruzzone of Universita degli Studi di Trento in Italy.

Under the lead of Bruzzone and the Italian Space Agency, JPL will provide the transmitter and receiver hardware for a radar sounder designed to penetrate the icy crust of Jupiter's moons Europa, Ganymede and Callisto to a depth of about 5 miles (9 kilometers). This will allow scientists to see for the first time the underground structure of these tectonically complex and unique icy worlds.

JUICE will carry 11 experiments developed by scientific teams from 15 European countries, the United States and Japan.

The spacecraft will orbit Jupiter for three years and travel past Callisto and Europa multiple times, then orbit Ganymede, a moon larger than the planet Mercury. JUICE will conduct the first thorough exploration of Jupiter since NASA's Galileo mission from 1989-2003.

By studying the Jupiter system, JUICE will look to learn more about the formation and evolution of potentially habitable worlds in our solar system and beyond.

"NASA is thrilled to collaborate with ESA on this exciting mission to explore Jupiter and its icy moons," said John Grunsfeld, NASA's associate administrator for science in Washington. "Working together with ESA and our other international partners is key to enabling future scientific progress in our quest to understand the cosmos."

The solar-powered spacecraft will carry cameras and spectrometers, a laser altimeter and an ice-penetrating radar instrument. The mission also will carry a magnetometer, plasma and particle monitors, and radio science hardware. The spacecraft is scheduled to arrive at the Jupiter system in 2030.

"The selection of JUICE's instruments is a key milestone in ESA's flagship mission to the outer solar system, which represents an unprecedented opportunity to showcase leading European technological and scientific expertise," said Alvaro Gimenez Canete, ESA's director of science and robotic exploration.

NASA invited researchers in 2012 to submit proposals for NASA-provided instruments for the mission. Nine were reviewed, with one selected to fly. NASA agreed to provide critical hardware for two of the 10 selected European-led instruments. NASA's total contribution to the JUICE mission is $100 million for design, development and operation of the instruments through 2033.

In addition to the radar team and instrument, the NASA contributions are:

-- Ultraviolet Spectrometer: The principal investigator is Randy Gladstone of Southwest Research Institute in San Antonio. This spectrometer will acquire images to explore the surfaces and atmospheres of Jupiter's icy moons and how they interact with the Jupiter environment. The instrument also will determine how Jupiter's upper atmosphere interacts with its lower atmosphere below, and the ionosphere and magnetosphere above. The instrument will provide images of the aurora on Jupiter and Ganymede.

-- Particle Environment Package: The principal investigator is Stas Barabash of the Swedish Institute of Space Physics. The U.S. lead is Pontus Brandt of the Johns Hopkins University Applied Physics Laboratory (APL) in Laurel, Md. Under the lead of Barabash and the Swedish National Space Board, APL will provide instruments to this suite to measure the neutral material and plasma that are accelerated and heated to extreme levels in Jupiter's fierce and complex magnetic environment.

NASA's Science Mission Directorate conducts a wide variety of research and scientific exploration programs for Earth studies, space weather, the solar system and the universe. The New Frontiers Program Office at NASA's Marshall Space Flight Center in Huntsville, Ala., will manage the NASA contributions. JUICE is the first large-class mission in ESA's Cosmic Vision 2015-2025 Program.

For more information on NASA planetary programs, visit: http://www.nasa.gov .

For more information about the JUICE mission, visit: http://sci.esa.int/juice .

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The above story is reprinted from materials provided by NASA/Jet Propulsion Laboratory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/vfUjp6hAClM/130221214216.htm

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Thursday, February 21, 2013

Trump Twitter mystery! Who hacked The Donald?

In what appears to be the latest in a minor wave of attacks on Twitter accounts belonging to out-sized corporate entities, an out-of-character tweet from Donald Trump's verified account set the Internet abuzz, and then disappeared, shortly before noon ET on Thursday.

"These hoes think they classy, well that's the class I'm skippen," read the suspect remark issued from @realDonaldTrump. It was a glaring non sequitur following tweets such as "Republicans must be careful with immigration?don?t give our country away," and "Wow, Macy's numbers just in-Trump is doing better than ever ? thanks for your great support!"

"Yes, obviously the account has been hacked and we are looking for the perpetrator," Rhona Graff, senior vice president, assistant to the president of the Trump Organization, told NBC News via email.

This confirmation was quickly echoed by Trump himself, in a tweet that read, "My Twitter has been seriously hacked ? and we are looking for the perpetrators."

Cut off after a single rogue tweet, the Trump Twitter anomaly was far shorter than the Burger King and Jeep takeovers earlier this week. On Monday, Burger King's Twitter account was hacked and renamed McDonalds, and over the course of a hour, sent out 53 tweets (and garnered 73,421 retweets) making light of the situation. The Tuesday attack on Jeep's Twitter account ? which included the erroneous announcement that the car maker had been taken over by Cadillac ? ceased after just 10 minutes and 13 tweets.

Soon after @Jeep regained control, the Twitter accounts of MTV and BET appeared to be compromised. The MTV account tweeted claims the network had been taken over by BET, and BET tweeted it was now owned by MTV. This turned out to be a publicity stunt by the networks, both owned by Viacom. As NBC News reported on Tuesday, the account of a PR representative warned of the hack ahead of time on Twitter and then both MTV and BET copped to the scheme after the "hack."

NBC News has asked the Trump Organization how Trump was able to regain control of his Twitter account so quickly, and will update this story if we receive a response.

Helen A.S. Popkin goes blah blah blah about the Internet. Tell her to get a real job on Twitterand/or Facebook.

Source: http://www.nbcnews.com/technology/technolog/trump-twitter-mystery-who-hacked-donald-1C8462918

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Wednesday, February 20, 2013

Shiites bury their dead in troubled Pakistani city

QUETTA, Pakistan (AP) ? Pakistani Shiites buried their kin killed in a massive bombing last weekend in the southwestern city of Quetta but the funeral on Wednesday was marred by gunfire as both protesters and police fired into the air.

Shiite Muslims have increasingly come under attack in this Sunni Muslim-dominated country where many extremists do not consider them to be true Muslims.

After Saturday's bombing killed 89 people, Pakistani Shiites refused to bury their dead for three days and demanded government action. The tension evident at the funeral suggested that recent government attempts to address the problem may not be enough to appease them.

Mourners on Wednesday lowered the bodies of 60 of the victims, wrapped in white cloth, into a long line of graves dug out at the local Shiite cemetery in Quetta.

Shiite community leader Qayum Changezi said tensions broke out after angry relatives of the deceased pelted police and government officials with stones. He said the protesters were demanding that the bodies not be buried until the Pakistani army leads a crackdown against the militant groups.

Both police and relatives fired into the air, the relatives in anger and the police to disperse the crowd, said police officer Fayaz Sumbal.

Changezi said the melee escalated as female relatives of the deceased blocked a main highway close to the graveyard, refusing to leave.

There's been no indication that the army would take control of the city, another longtime demand of protesters. But the government announced on Monday that paramilitary forces began an operation against the anti-Shiite militant group Lashkar-e-Jhangvi, which claimed responsibility for Saturday night's blast, and other militant groups.

The government also replaced the top police officer in Baluchistan on Tuesday. And Fayaz Sumbal, deputy police chief in Quetta has also been ordered to replace the chief of police operations in Quetta.

Shiites have criticized police and paramilitary forces under control of the Interior Ministry in Quetta for failing to protect the minority sect, which comprises up to 20 percent of the country's population of 180 million.

__

Associated Press writer Rebecca Santana in Islamabad contributed to this report.

Source: http://news.yahoo.com/shiites-bury-dead-troubled-pakistani-city-073628141.html

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Pathway controlling cell growth revealed

Feb. 18, 2013 ? A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state.

The finding has revealed an important mechanism controlling the growth of rapidly-dividing cells that may ultimately lead to the development of new treatments for diseases including cancer.

The discovery was made by Associate Professor Joan Heath, Dr Yeliz Boglev and colleagues at the Melbourne-Parkville Branch of the Ludwig Institute for Cancer Research. Dr Kate Hannan, Associate Professor Rick Pearson and Associate Professor Ross Hannon at the Peter MacCallum Cancer Centre, also contributed to the work, which was published in the journal PLOS Genetics this month.

Associate Professor Heath, a Ludwig Institute Member who recently transferred her research group to the Walter and Eliza Hall Institute, said the discovery was made while studying zebrafish embryos that harbour genetic mutations which prevent rapid cell growth during organ development. "Zebrafish embryos provide us with a great laboratory model for these studies because they are transparent, an attribute that allows us to track the growth of rapidly developing organs in live animals under a simple microscope. Moreover, the genes controlling growth and proliferation of developing tissues are essentially identical in zebrafish and humans, and are known to be frequently commandeered by cancer cells."

"We discovered that a mutation in a relatively under-studied gene called pwp2h leads to the faulty assembly of ribosomes, the 'protein factories' of cells, and stops cells from dividing," she said. "What was intriguing was that cells under stress from ribosome failure did not die. Instead, the cells switched on a survival mechanism called autophagy and began obtaining nutrients by digesting their own intracellular components."

Ribosomes are large molecular machines in cells that manufacture proteins, and are critical for cell growth and division. Currently, there is great interest in developing therapeutics to block ribosome production, as a strategy to prevent cancer cells from dividing.

"Our research could have implications for this type of cancer treatment," Associate Professor Heath said. "We showed that when ribosome assembly is disrupted, cells stop growing as desired, but to our surprise they enter a survival state. An anti-cancer treatment that inadvertently promotes the survival of cancer cells through autophagy is clearly not desirable. However, our findings in zebrafish show that if ribosome assembly is blocked and, at the same time, autophagy is inhibited, cells die rapidly. It is possible that a combination of inhibitors that block ribosome function and autophagy could provide an effective anti-cancer treatment," she said.

Associate Professor Heath's group is continuing its research at the Walter and Eliza Hall Institute, examining other genetic mutations in zebrafish that disrupt cell growth and division. "We are keen to enhance our approach by applying existing research technologies at the institute," she said. "We have identified a number of cellular processes that rapidly dividing cells -- including cancer cells -- depend on, and the next stage is to test whether they could provide new targets for anti-cancer therapy."

The research was supported by the National Health and Medical Research Council and the Victorian Government.

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Journal Reference:

  1. Yeliz Boglev, Andrew P. Badrock, Andrew J. Trotter, Qian Du, Elsbeth J. Richardson, Adam C. Parslow, Sebastian J. Markmiller, Nathan E. Hall, Tanya A. de Jong-Curtain, Annie Y. Ng, Heather Verkade, Elke A. Ober, Holly A. Field, Donghun Shin, Chong H. Shin, Katherine M. Hannan, Ross D. Hannan, Richard B. Pearson, Seok-Hyung Kim, Kevin C. Ess, Graham J. Lieschke, Didier Y. R. Stainier, Joan K. Heath. Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis. PLOS Genetics, 07 Feb 2013 DOI: 10.1371/journal.pgen.100327

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/IRXx0LH_DEQ/130218092713.htm

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Monday, February 18, 2013

Sister can't figure out Windows 8 (2 replies)

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